Cheap American Airlines flights Orlando (MCO) to San Diego (SAN)

Make use of the "Price (lowest to highest)" filter on Expedia to search for cheap American Airlines round-trip flights from MCO to SAN. Affordable one-way options are available as well.*

*These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

January is one of the most affordable months to fly to San Diego with American Airlines. You could also find fantastic deals on one-way and round-trip fares in November.

Click on our "Nonstop" filter when looking for direct American Airlines flights from MCO to SAN. It's also a great way to compare other airlines offering the same nonstop route.

Hop on an American Airlines flight from Orlando Intl. Airport (MCO) to San Diego, and you're most likely to arrive at San Diego Intl. Airport (SAN). This is the airline's primary hub in this city.

Changes are often free within 24 hours of making a booking, but your airline may charge a fee after that. For more details about modifying your flights, go to your "Trips," select your flight and click on "Manage Booking." If you'd like the flexibility to make changes without additional costs, check the "No cancel fee" or "Changes included" filter when planning your next escape.