Cheap American Airlines flights McAllen (MFE) to Denver (DEN)

Scoring cheap one-way American Airlines flights from MFE to DEN on Expedia is a cinch — just filter by "Price (lowest to highest)." Alternatively, check out our affordable round-trip fares for your next exciting vacation.*

*These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

American Airlines flights to Denver are typically cheaper in the quieter months of January and November. Whether you're searching for a one-way or round-trip ticket, you could find a better deal then.

Use the "Nonstop" filter when searching for direct American Airlines flights from MFE to DEN. You can also compare other carriers servicing the same nonstop trip.

Board an American Airlines flight from Miller Intl. Airport (MFE) to Denver, and you'll probably land at Denver Intl. Airport (DEN). This is the airline's main hub here.

It's generally possible to cancel or reschedule your flight, although there may be additional charges if your booking was made more than 24 hours ago. Prefer to keep your options open? Use our "No cancel fee" and "Changes included" filters to find flights that won't charge extra if you need to adjust your plans. To make modifications, head to "Trips," select your flight and click on "Manage Booking" for further information.