The location of the hotel lets you visit most of the tourist places in New York, is near the 50th metro station, and also near some of the bus stops. The neighborhood is quiet and safe, you can really enjoy the city without a problem.
It is true in the evening the neighborhood is loud but what do you expect from a city that never sleeps, there is a bar near the hotel that is always playing loud music, but at 10:00 pm the bar closes and noise stops, so there is no problem to have a long sleep.
My only concern is about the breakfast, the variety of the options to choose from is limited and sometimes even being at the beginning of the breakfast hour you couldn´t choose what you want but only what is left. Also, the number of tables to have breakfast is really reduced, there were only six tables for all the people that are staying in the hotel; so you will have to have breakfast at your room or use the lobby area.